Developing Epithelia: What the Eye Cannot Grasp

Expression of DM-GRASP/BEN in the developing mouse spinal cord and various epithelia

The expression pattern of the immunoglobulin DM-GRASP/BEN gene was studied in the mouse embryo using in situ hybridization. DM-GRASP/BEN is expressed in the spinal cord in a subset of motoneurons expressing Islet-1, and non homogeneously in the dorsal root ganglia (DRG). In contrast, it's expression is homogeneous in the vestibulo-cochlear and trigemminal ganglia. DM-GRASP/BEN is also expressed...

Language beyond Our Grasp: What Mirror Neurons Can, and Cannot, Do for Language Evolution

And, I would add, we must also take care to analyse properly the nature of language itself. Several recent papers (Rizzolatti and Arbib, 1998; Arbib, 2001; Arbib, 2002) suggest that the discovery of mirror neurons helps us to understand in some more detail how human language evolved. The present paper tries to explore and continue further the development of ideas in these papers(1). Two main is...

What Money Cannot Buy? Compassion in Healthcare: A Response to the Recent Commentaries

Simulating what cannot be simulated

The background to these notes is the expectation that mathematical modelling and simulation is going to play increasingly important role in the understanding of the organization and control of genetic-, metabolic-, and signalling pathways. I am going to argue that for modelling and simulation to help our understanding of cellular dynamics, the current practice of experimental design has to chan...

See What You Cannot See

DU. A national study of chronic disease prevalence and access to care in uninsured U. Engelgau MM. Self-management education for adults with type 2 diabetes: A meta-analysis of the effect on glycemic control. The health status of patients of a student-run free medical clinic in inner-city Buffalo, NY. Insuring the uninsured: A student-run initiative to improve access to care in an urban communi...